SUV4-20H HISTONE METHYLTRANSFERASES PROMOTE NEUROECTODERMAL DIFFERENTIATION BY SILENCING THE PLURIPOTENCY-ASSOCIATED OCT-25 GENE.

Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene.

Post-translational modifications (PTMs) of histones exert fundamental roles in regulating gene expression.During development, groups of PTMs are constrained by unknown mechanisms into combinatorial patterns, which facilitate transitions from uncommitted embryonic cells into differentiated somatic cell lineages.Repressive histone modifications such

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